QUERY GENE

HNGC Gene Symbol [e.g. A2M]:



OR


Entrez ID [e.g. 15]:



OR


Uniprot Swissprot Accession ID [e.g. A1A4Y4]:



Prediction Probability

Probability of Association

Attribute Group 1

Amino Acid Composition

Alanine(A)    Cysteine(C)      Aspartic Acid(D)      Glutamic Acid(E)      Phenylalanine(F)
Glycine(G)    Histidine(H)      Isoleucine(I)      Lysine(K)      Leucine(L)
Metheonine(M)    Asparagine(N)      Proline(P)      Glutanine(Q)      Arginine(R)
Serine(S)    Threonine(T)      Valine(V)      Tryptophane(W)      Tyrosine(Y)

Attribute Group 2

*Hydrophobicity   *Normalized Vander
Waal Volume
   *Polarity    
  
Polar Amino Acid(R,K,E,D,Q,N)   0-2.78(G,A,S,T,P,D)   4.9-6.2(L,I,P,W,C,M,V,Y)    
Neutral Amino Acid(G,A,S,T,P,H,Y)   2.95-4.0(N,V,E,Q,I,L)   8.0-9.2(P,A,T,G,S)    
Hydrophobic Amino Acid (C,L,V,I,M,P,W)   4.03-8.08(M,H,K,F,R,Y,W)   10.4-13.2 (H,Q,R,K,N,E,D)    


*Charge       *Secondary
Structure
    
  
Positive(K,R)       Helix(E,A,L,M,Q,K,R,H)      
Neutral(A,N,C,Q,G,H,I,L,M,F,P,S,T,W,Y,V)       Strand(V,I,V,C,W,F,T)      
Negetive(D,E)       Coil(G,N,P,S,D)      


*Sovlent
Accessibility
     *Polarizablity      
Burried(A,L,F,C,G,I,V,W)     0-1.08 (G,A,S,D,T)      
Exposed(P,K,Q,E,N,D)     0.128-0.186 (C,P,N,V,E,Q,I,L)      
Intermediate(MPSTHY)     0.219-0.407 (K,M,H,F,R,Y,W)      


* percenage frequency of defined amino acids in physiochemical properties

Attribute Group 3

Sub cellular localization of protein
Cell junction
Centrosome
Cytoplasm
Endoplasmic Reticulum
Focal Adhesions
Golgi Apperatus
Mitochondria
Nucleus
Plasma Membrane
Vesicle
Unknown

Attribute Group 4

Network Properties
Betweenness centrality
Closeness centrality
Clustering Coefficient
Degree